bisphosphonate

bisphosphonate
a) Any of a class of organic compounds having two phosphate groups attached to a single carbon atom
b) Several pharmaceuticals, having this structure, that are used to treat Pagets disease by restricting bone loss

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  • Bisphosphonate — Bisphosphonate,   Wirkstoffgruppe zur Behandlung der Osteoporose. In den Bisphosphonaten ist das Brückensauerstoffatom zwischen den beiden Phosphoratomen von Pyrophosphat, einem physiologischen Knochenbestandteil, durch ein Kohlenstoffatom… …   Universal-Lexikon

  • bisphosphonate — /bis fosˈfə nāt/ noun Any of a family of drugs primarily used to prevent and treat osteoporosis ORIGIN: L bis twice, and ↑phosphate …   Useful english dictionary

  • Bisphosphonate — Basisstruktur der Bisphosphonate Bisphosphonate (auch Diphosphonate) sind chemische Verbindungen, die über zwei Phosphonat Gruppen verfügen. Inhaltsverzeichnis 1 …   Deutsch Wikipedia

  • Bisphosphonate — Basic structure of a bisphosphonate on top. To compare the structure of pyrophosphate below. Note the similarity in structure. Bisphosphonates (also called diphosphonates) are a class of drugs that prevent the loss of bone mass, used to treat… …   Wikipedia

  • Bisphosphonate — Les bisphosphonates[1], ou diphosphonates, sont des molécules indiquées dans le traitement de l’ostéoporose et dans certains cas de métastases osseuses. Les bisphosphonates sont le traitement de prédilection pour l’hypercalcémie paranéoplasique… …   Wikipédia en Français

  • Bisphosphonate-associated osteonecrosis of the jaws — Bisphosphonate associated osteonecrosis of the jaws, often abbreviated as BON, is a recently discovered dental phenomenon that may lead to surgical complication in the form of impaired wound healing following oral or periodontal surgery or… …   Wikipedia

  • bisphosphonate — bis·phos·pho·nate (.)bī fäs fə .nāt n any of a group of carbon substituted analogs (as etidronate) of pyrophosphate that are potent inhibitors of osteoclast mediated bone resorption * * * bis·phos·pho·nate (bis fosґfə nāt) diphosphonate …   Medical dictionary

  • bisphosphonate — A type of drug used to treat osteoporosis and the bone pain caused by some types of cancer. Also called diphosphonate …   English dictionary of cancer terms

  • bisphosphonate —  n.m. Médicament contre l ostéoporose …   Le dictionnaire des mots absents des autres dictionnaires

  • Bisphosphonatassoziierte Knochennekrose — Bisphosphonate assoziierte Knochennekrosen, engl. bisphosphonate associated osteonecrosis of the jaw (BONJ, ONJ) sind Nekrosen der Kieferknochen, die gehäuft bei Patienten auftreten, die zuvor mit Bisphosphonaten behandelt wurden. Auslöser ist in …   Deutsch Wikipedia

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