trovafloxacin

trovafloxacin
A broad-spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.

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  • Trovafloxacin — drugbox IUPAC name = 7 (6 amino 3 azabicyclo [3.1.0] hex 3 yl) 1 (2,4 difluorophenyl) 6 fluoro 4 oxo [1,8] naphthyridine 3 carboxylic acid CAS number = 147059 72 1 ATC prefix = J01 ATC suffix = MA13 ATC supplemental = PubChem = 62959 DrugBank =… …   Wikipedia

  • trovafloxacin mesylate — tro·va·flox·a·cin mes·y·late (tro″və flokґsə sin) a fluoronaphthyridone antibacterial, effective against a broad spectrum of gram positive and gram negative organisms, used in the treatment of serious infections caused by… …   Medical dictionary

  • Kano Trovafloxacin trial litigation — In 1996 Pfizer conducted tests of the drug trovafloxacin in Nigeria on one hundred children (Source of number: http://www.irinnews.org/PrintReport.aspx?ReportId=72601 link leads to UN IRIN news report), five of whom died. Many others suffered… …   Wikipedia

  • Alatrofloxacin — Drugbox IUPAC name = 7 [(1 R ,5 S ) 6 { [(2 S ) 1 { [(2 S ) 2 aminopropanoyl] amino} 1 oxopropan 2 yl] amino} 3 azabicyclo [3.1.0] hexan 3 yl] 1 (2,4 difluorophenyl) 6 fluoro 4 oxo 1,8 naphthyridine 3 carboxylic acid width = 250 CAS number =… …   Wikipedia

  • Pfizer — Infobox Company company name = Pfizer, Inc. company company type = Public (NYSE: [http://www.nyse.com/about/listed/lcddata.html?ticker=PFE PFE] ) company slogan = Working for a healthier world foundation = Brooklyn, NY, USA (1849) location =… …   Wikipedia

  • Hepatotoxicity — Alternative names Toxic liver disease Toxin induced liver disease Drug induced liver disease Drug induced liver damage Hepatogenous poisoning Subordinate terms Toxic hepatitis Toxin induced hepatitis Drug induced hepatitis Drug induced hepatic… …   Wikipedia

  • Melioidosis — Classification and external resources ICD 10 A24.1 A24.4 ICD 9 …   Wikipedia

  • Norfloxacin — Systematic (IUPAC) name 1 ethyl 6 fluoro 4 oxo 7 piperazin 1 yl 1H quinoline 3 carboxylic acid Clinical data Trade names …   Wikipedia

  • Moxifloxacin — Systematic (IUPAC) name …   Wikipedia

  • Pefloxacin — Systematic (IUPAC) name 1 ethyl 6 fluoro 7 (4 methylpiperazin 1 yl) 4 oxo quinoline 3 carboxylic acid Clinical data Pregnancy cat …   Wikipedia

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