farnesyltransferase

farnesyltransferase
One of the three enzymes in the prenyltransferase group, believed to play an important role in development of progeria and various cancers.

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  • Farnesyltransferase — is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15 carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four amino acid sequence at the carboxyl terminus of a protein.… …   Wikipedia

  • Farnesyltransferase — Vorhandene Strukturdaten: s. UniProt Masse/Länge Primärstruktur …   Deutsch Wikipedia

  • Farnesyltransferase inhibitor — The farnesyltransferase inhibitors (FTIs) are a class of experimental cancer drugs that target protein farnesyltransferase with the downstream effect of preventing the proper functioning of the Ras (protein), which is commonly abnormally active… …   Wikipedia

  • Protohäm-IX-Farnesyltransferase — Masse/Länge Primärstruktur <443 Aminosäuren …   Deutsch Wikipedia

  • Farnesyl-diphosphate farnesyltransferase — protein Name=farnesyl diphosphate farnesyltransferase 1 caption= width= HGNCid=3629 Symbol=FDFT1 AltSymbols= EntrezGene=2222 OMIM=184420 RefSeq=NM 004462 UniProt=P37268 PDB= ECnumber=2.5.1.21 Chromosome=8 Arm=p Band=23.1 LocusSupplementaryData=… …   Wikipedia

  • Protein farnesyltransferase — In enzymology, a protein farnesyltransferase (EC number|2.5.1.58) is an enzyme that catalyzes the chemical reaction:farnesyl diphosphate + protein cysteine ightleftharpoons S farnesyl protein + diphosphateThus, the two substrates of this enzyme… …   Wikipedia

  • FNTA — Farnesyltransferase, CAAX box, alpha, also known as FNTA, is a human gene.cite web | title = Entrez Gene: FNTA farnesyltransferase, CAAX box, alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2339|… …   Wikipedia

  • FNTB — Farnesyltransferase, CAAX box, beta, also known as FNTB, is a human gene.cite web | title = Entrez Gene: FNTB farnesyltransferase, CAAX box, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2342|… …   Wikipedia

  • FNTA — farnesyltransferase alpha …   Medical dictionary

  • FNTB — farnesyltransferase beta …   Medical dictionary

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