- bioorthogonal
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Describing biochemical research techniques for selectively labelling biomolecules that are independent of the detailed structure of the host molecule
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bioorthogonal
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Bioorthogonal chemical reporter — In chemical biology, a bioorthogonal chemical reporter is a tool for tagging and visualizing biomolecules. Prescher Bertozzi defined bioorthogonal chemical reporters as non native, non perturbing chemical handles that can be modified in living… … Wikipedia
Chemical biology — is a scientific discipline spanning the fields of chemistry and biology that involves the application of chemical techniques and tools, often compounds produced through synthetic chemistry, to the study and manipulation of biological systems.… … Wikipedia
Copper-free click chemistry — is a bioorthogonal reaction first developed by Carolyn Bertozzi as an activated variant of an azide alkyne Huisgen cycloaddition, based on the work by Sharpless et. al. Unlike the CuAAC, Cu free click chemistry has been modified to be… … Wikipedia
Carolyn Bertozzi — im November 2011 Carolyn Ruth Bertozzi (* 19. Mai 1966 in Boston, Massachusetts) ist eine US amerikanische Biochemikerin und Hochschullehrerin. Sie ist T.Z. and Irmgard Chu Distinguished Professor für Chemie und Professorin für Molekular und… … Deutsch Wikipedia
Биоортогональные реакции — К биоортогональным реакциям относятся любые химические реакции, которые могут протекать внутри живых систем, не мешая естественным биохимическим процессам.[1][2][3] Термин был предложен Каролин Бертоцци (Carolyn R. Bertozzi) в 2003 году.[4] Уже к … Википедия
Азид-алкиновое циклоприсоединение — Азид алкиновое циклоприсоединение реакция между азидами и алкинами с образованием 1,2,3 триазолов. Реакция впервые была описана Михаэлем в 1893 г., который обнаружил, что при нагреве эфирного раствора фенилазида и диметилового эфира… … Википедия
Azide — The azide anion The azide functional group Azide is the anion with the formula N3−. It is the conjugate base of hydrazoic acid. N3− is a linear … Wikipedia
Click chemistry — is a chemical philosophy introduced by K. Barry Sharpless of The Scripps Research Institute, in 2001[1][2] and describes chemistry tailored to generate substances quickly and reliably by joining small units together. This is inspired by the fact… … Wikipedia
