marimastat

marimastat
A novel matrix metalloprotease inhibitor once proposed for cancer treatment

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  • marimastat — An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Marimastat is a matrix metalloproteinase inhibitor …   English dictionary of cancer terms

  • British Biotech — Infobox Defunct Company company name = British Biotech plc (LSE:BBG Nasdaq:BBIOY) company fate = Merged successor = company merged into Vernalis foundation = 1986 defunct = 2003 location = Oxford, United Kingdom industry = Biotechnology key… …   Wikipedia

  • Matrix metalloproteinase — Cell surface associated MT1 MMP (MMP14), Green fluorescent protein (GFP) fused to the C term produces a signal on the surface of the cell[1] Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases; other family members are adamalysins …   Wikipedia

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • Angiogenesis inhibitor — An angiogenesis inhibitor is a substance that inhibits angiogenesis (the growth of new blood vessels). It can be endogenous or come from outside as drug or a dietary component. Every solid tumor (in contrast to liquid tumors like leukemia) needs… …   Wikipedia

  • Matrix metalloproteinase inhibitor — A matrix metalloproteinase inhibitor (MMPI) inhibits matrix metalloproteinases. As they inhibit cell migration they have antiangiogenic effects. They may be both endogenous and exogenous. The most notorious endogenous metalloproteinases are… …   Wikipedia

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