discodermolide

discodermolide
A natural polyketide that is a potent inhibitor of tumour cell growth.

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  • Discodermolide — IUPAC name (+) Discodermolide …   Wikipedia

  • discodermolide — /dis kō dûrˈmə līd/ noun A drug used in experimental treatments for cancer ORIGIN: Discodermia dissoluta, name of a sponge from which it is derived …   Useful english dictionary

  • discodermolide — Anti tumour drug (a poly hydroxylated alkatetraene lactone) that, like taxol, promotes formation of stable bundles of microtubules and competes with taxol for binding to polymerized tubulin. Isolated from the marine sponge, Discodermia dissoluta …   Dictionary of molecular biology

  • Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …   Wikipedia

  • Discodermolida — Saltar a navegación, búsqueda discodermolida …   Wikipedia Español

  • Secondary metabolite — Secondary metabolites are organic compounds that are not directly involved in the normal growth, development or reproduction of organisms. Unlike primary metabolites, absence of secondary metabolities results not in immediate death, but in long… …   Wikipedia

  • Aldol reaction — The aldol reaction is a powerful means of forming carbon–carbon bonds in organic chemistry.[1][2][3] Discovered independently by …   Wikipedia

  • Polyketide — Polyketides are secondary metabolites from bacteria, fungi, plants, and animals. Polyketides are biosynthesized by the polymerization of acetyl and propionyl subunits in a similar process to fatty acid synthesis (a Claisen condensation). cite… …   Wikipedia

  • Natural product — Paclitaxel (Taxol) is a natural product derived from the Yew tree.[1] A natural product is a chemical compound or substance produced by a living organism found in nature that usually has a pharmacological or biological activity for use in… …   Wikipedia

  • Epothilone — The epothilones are a new class of cytotoxic molecules identified as potential chemotherapeutic drugs. [Vincent T. DeVita, Jr., MD; Samuel Hellman, MD; and Steven A. Rosenberg, MD, PhD (2004) Cancer: Principles And Practice Of Oncology (7th… …   Wikipedia

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