holoprosencephaly

holoprosencephaly
A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.
See Also: alobar, semilobar, lobar, premaxillary agenesis, cyclopia, ethmocephaly, cebocephaly

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  • Holoprosencephaly — A disorder characterized by the failure of the prosencephalon (the forebrain of the embryo) to develop. During normal development, the forebrain is formed and the face begins to develop in the fifth and sixth weeks of pregnancy. Holoprosencephaly …   Medical dictionary

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