- bispecific
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Describing an antibody that binds to two different antigens
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bispecific
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Bispecific monoclonal antibody — A bispecific monoclonal antibody is a monoclonal antibody that binds two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory. External links *… … Wikipedia
Bispecific antibody — A bispecific antibody is a monoclonal antibodies which is designed to bind to two different antigens.One benefit of this approach is that it is possible for such an antibody to simultaneously bind to a cytotoxic cell (using a receptor like CD3)… … Wikipedia
bispecific antibody — antibody in which each of two antigen binding sites is specific for separate antigenic determinants. It is an artificial antibody produced in the laboratory, formed by reassociating half molecules of two different antibody specificities to form a … Medical dictionary
bispecific antibody — An antibody developed in the laboratory to recognize more than one protein on the surface of different cells. Examples include bispecific antibodies 2B1, 520C9xH22, mDX H210, and MDX447 … English dictionary of cancer terms
bispecific monoclonal antibody — A monoclonal antibody that binds two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory … English dictionary of cancer terms
hybrid antibody — bispecific a … Medical dictionary
Bispezifischer Antikörper — Ein bispezifischer Antikörper (Abkürzung: BsMAb von engl. bispecific monoclonal antibody), auch als Hybrid Antikörper bezeichnet, ist ein Immunkonjugat, das aus Bestandteilen von zwei unterschiedlichen monoklonalen Antikörpern aufgebaut sind.… … Deutsch Wikipedia
Chemically linked Fab — Example of chemically linked Fabs: two Fab fragments linked with a thioether, resulting in a F(ab )2. The molecule is bound to a tumour cell via the tumour antigen CD30 and to a macrophage via an Fc receptor. Two chemically linked fragments… … Wikipedia
Single-chain variable fragment — Rotating scFv fragment with highlighted complementary determining regions (CDRs) … Wikipedia
Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… … Wikipedia
