One of the most potent naturally-produced antibiotics known, first obtained from Streptomyces cattleya in 1976.

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  • Thienamycin — Chembox new Name = Thienamycin ImageFile = Thienamycinsmallish.png ImageSize = 150px IUPACName = ( 5R,6S ) 3 [(2 Aminoethyl)thio] 6 [( 1R ) 1 hydroxyethyl] 7 oxo 1 azabicyclo [3.2.0] hept 2 ene 2 carboxylic acid Section1 = Chembox Identifiers… …   Wikipedia

  • Thienamycin — Carbapeneme, ursprünglich als Thienamycine bezeichnet, sind β Lactam Antibiotika mit breitem Wirkungspektrum. Vertreter sind Imipenem, Ertapenem, Meropenem und Doripenem. Imipenem ist stark nephrotoxisch (nierenschädlich). Zur Nierenprotektion… …   Deutsch Wikipedia

  • thienamycin — The first member of a family of des thia carbapenem nucleus antibiotics having a thioethylamine side chain on the enamine portion of the fused 5 membered ring. * * * thi·en·a·my·cin (thi en″ə miґsin) an antibacterial produced by… …   Medical dictionary

  • Imipenem — Systematic (IUPAC) name (5R,6S) 6 [(1R) 1 hydroxyethyl] 3 ({2 [(iminomethyl)amino]ethyl}thio) 7 oxo 1 azabicyclo[3.2.0]hept 2 ene 2 carboxylic acid Clinical data …   Wikipedia

  • actinomycetes — n. 1. branched gram positive bacteria, often found in soil, some of which are pathogenic for humans and animals. Note: some species have been found to produce metabolites which are useful in medicine. Many species of these bacteria have been… …   The Collaborative International Dictionary of English

  • Carbapenem — Carbapenems are a class of beta lactam antibiotics with a broad spectrum of antibacterial activity, and have a structure which renders them highly resistant to beta lactamases. Carbapenem antibiotics were originally developed from thienamycin, a… …   Wikipedia

  • Pyrroline — Pyrrolines, also known under the name dihydropyrroles, are three different heterocyclic organic chemical compounds which differ in the position of the double bond. Pyrrolines are formally derived from the aromate pyrrole by hydrogenation. 1… …   Wikipedia

  • carbapenems — A class of broad spectrum bactericidal β lactam antibiotics that bind to the penicillin binding protein 2 and thereby interfere with cell wall structure; they are highly resistant to β lactamases and easily penetrate bacterial walls. * * *… …   Medical dictionary

  • imipenem — A thienamycin antibiotic with broad spectrum activity used, in combination with cilastin, to treat a variety of infections. * * * im·i·pen·em .im ə pen əm n a semisynthetic beta lactam C12H17N3O4S·H2O that is derived from an antibiotic produced… …   Medical dictionary