treadmilling

treadmilling
The apparent locomotion of certain cellular filaments by adding protein subunits at one end, and removing them at the other

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  • Treadmilling — is a phenomenon observed in many cellular cytoskeletal filaments, especially in actin filaments and microtubules. It occurs when one end of a filament grows in length while the other end shrinks resulting in a section of filament seemingly moving …   Wikipedia

  • Treadmilling — Als Treadmilling wird ein Phänomen bei der Polymerisation von Aktinfilamenten im Cytoplasma eukaryotischer Zellen bezeichnet. Wenn das Aktinpolymer den steady state erreicht hat, erfolgt ein Nettoaufbau von Aktin am Plusende des Aktinfilaments.… …   Deutsch Wikipedia

  • treadmilling — Name given to the proposed process in microtubules in which there is continual addition of subunits at one end, and disassembly at the other, so that the tubule stays of constant length, but individual subunits move along. Could in principle be… …   Dictionary of molecular biology

  • Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …   Wikipedia

  • Microfilament — Actin cytoskeleton of mouse embryo fibroblasts, stained with Fluorescein isothiocyanate phalloidin Microfilaments ( or actin filaments) are the thinnest filaments of the cytoskeleton, a structure found in the cytoplasm of all eukaryotic cells.… …   Wikipedia

  • Katanin — is a microtubule severing AAA protein. It is named after the Japanese sword, katana. Katanin is a heterodimeric protein first discovered in sea urchins. It contains a 60 kDa ATPase subunit, which functions to sever microtubules. This subunit… …   Wikipedia

  • Микротрубочки — Микротрубочки  белковые внутриклеточные структуры, входящие в состав цитоскелета. Микротрубочки представляют собой полые внутри цилиндры диаметром 25 нм. Длина их может быть от нескольких микрометров до, вероятно, нескольких миллиметров в… …   Википедия

  • Intermediate filament — Intermediate filaments (IFs) are cytoskeletal structures formed by members of a family of related proteins called keratin. Intermediate filaments have a diameter of 12 nanometers, which is between that of actin (microfilaments) and microtubules.… …   Wikipedia

  • Grind (gaming) — Grinding is a term used in computer gaming to describe the process of engaging in repetitive and/or non entertaining gameplay in order to gain access to other features within the game.cite web | url =… …   Wikipedia

  • Growth cone — Image of a fluorescently labeled growth cone extending from an axon F actin (red) microtubules (green). A growth cone is a dynamic, actin supported extension of a developing axon seeking its synaptic target. Their existence was originally… …   Wikipedia

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