neuroactive steroid

neuroactive steroid
Any of several steroids, synthesized in the myelinating glial cells, which alter neuronal excitability through interaction with neurotransmitter-gated ion channels.

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  • Neuroactive steroid — Neuroactive steroids (or neurosteroids) rapidly alter neuronal excitability through interaction with neurotransmitter gated ion channels.[1][2] In addition, these steroids may also exert effects on gene expression via intracellular steroid… …   Wikipedia

  • GABAA receptor — The GABAA receptor is one of two ligand gated ion channels responsible for mediating the effects of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain. In addition to the GABA binding site, the GABAA receptor… …   Wikipedia

  • Minaxolone — Systematic (IUPAC) name (2β,3α,5α,11α) 11 (dimethylamino) 2 ethoxy 3 hydroxypregnan 20 one Clinical data Pregnancy cat. & …   Wikipedia

  • Stéroïde neuroactif — Un stéroïde neuroactif (ou neurostéroide) est un type de stéroïde qui altère rapidement l excitabilité neuronale par une interaction avec les récepteurs ionotropes[1],[2]. De plus, ces stéroïdes peuvent exercer un effet sur l expression génétique …   Wikipédia en Français

  • Org 21465 — Systematic (IUPAC) name [2 [(2S,3S,5S,8S,9S,10S,13S,14S,17S) 2 (2,2 dimethylmorpholin 4 yl) 3 hydroxy 10,13 dimethyl 11 oxo 1,2,3,4,5,6,7,8,9,12,14,15,16,17 tetradecahydrocyclopenta[a]phenanthren 17 yl] 2 oxoethyl]methanesulfonate …   Wikipedia

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  • Ganaxolone — Drugbox IUPAC name = 1 ​ [(3R,5S,8R,9S,10S,13S,14S,17S) ​3 ​hydroxy ​3,10,13 ​trimethyl ​1,2,4,5,6,7,8,9,11,12,14,15,16,17 ​tetradecahydrocyclopenta [a] phenanthren ​17 ​yl] ethanone width = 200 CAS number = 38398 32 2 CAS supplemental = ATC… …   Wikipedia

  • GABAC receptor — protein Name = gamma aminobutyric acid (GABA) receptor, rho 1 caption = width = HGNCid = 4090 Symbol = GABRR1 AltSymbols = EntrezGene = 2569 OMIM = 137161 RefSeq = NM 002042 UniProt = P24046 PDB = ECnumber = Chromosome = 6 Arm = q Band = 14… …   Wikipedia

  • Benzodiazepine withdrawal syndrome — ] Various studies have shown between 20–100% of patients prescribed benzodiazepines at therapeutic dosages long term are physically dependent and will experience withdrawal symptoms. [cite book |last= Ashton |first= CH |editor= A Baum, S. Newman …   Wikipedia

  • CCK-4 — Systematic (IUPAC) name (3S) 3 [(2S) 2 amino 3 phenylpropanamido] 3 {[(1S) 1 {[(1S) 1 carboxy 2 (indol 3 yl)ethyl]carbamoyl} 3 (methylsulfanyl)propyl]carbamoyl}propanoic acid Clinical data …   Wikipedia

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