nonsynonymous

nonsynonymous

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  • nonsynonymous substitution — nonsynonymous substitution. См. смысловая замена [нуклеотида]. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Nonsynonymous substitution — A nonsynonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitutions which do not alter amino acid sequences. As nonsynonymous substitutions result in a biological… …   Wikipedia

  • nonsynonymous — adj.; nonsynonymously, adv. * * * …   Universalium

  • nonsynonymous — non syn•on′y•mous adj. ly, adv …   From formal English to slang

  • nonsynonymous — adj.; nonsynonymously, adv …   Useful english dictionary

  • смысловая замена [нуклеотида] — nonsynonymous substitution смысловая замена [нуклеотида]. Мутационная замена нуклеотида в кодирующей последовательности, приводящая к изменению последовательности аминокислот в соответствующем белке кодируемом продукте; из за вырожденности… …   Молекулярная биология и генетика. Толковый словарь.

  • Ka/Ks ratio — In genetics, the Ka/Ks ratio (or ω, dN/dS), is the ratio of the rate of non synonymous substitutions (Ka) to the rate of synonymous substitutions (Ks), which can be used as an indicator of selective pressure acting on a protein coding gene.… …   Wikipedia

  • ATG16L1 — ATG16 autophagy related 16 like 1 (S. cerevisiae), also known as ATG16L1, is a human gene.cite journal | author = Zheng H, Ji C, Li J, Jiang H, Ren M, Lu Q, Gu S, Mao Y, Xie Y | title = Cloning and analysis of human Apg16L | journal = DNA… …   Wikipedia

  • Single nucleotide polymorphism — A single nucleotide polymorphism (SNP, pronounced snip ) is a DNA sequence variation occurring when a single nucleotide A, T, C, or G in the genome (or other shared sequence) differs between members of a species (or between paired chromosomes in… …   Wikipedia

  • McDonald–Kreitman test — The McDonald–Kreitman Test looks for ancient selection over long periods, as opposed to the steady accumulation of mutations that confer no selective advantage predicted by the Neutral theory. It was first devised by John McDonald and Martin… …   Wikipedia

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