thiopurine

thiopurine
Any of several types of sulfur derivative of a purine, some of which have medical applications

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  • Thiopurine — The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn s disease, rheumatoid arthritis) and organ transplant recipients.ee also* 6 mercaptopurine (6 MP) * 6… …   Wikipedia

  • Thiopurine methyltransferase — or thiopurine S methyltransferase (TPMT) is an enzyme (EC number|2.1.1.67) that methylates thiopurine compounds. The methyl donor is S adenosyl L methionine, which is converted to S adenosyl L homocysteine.This gene encodes the enzyme that… …   Wikipedia

  • thiopurine — thi·o·pu·rine (thi″o puґrēn) 1. a purine base in which a thiol group is found in place of one of the hydroxyl groups. 2. any of a group of drugs that include such a compound as part of their structure …   Medical dictionary

  • TPMT — thiopurine methyltransferase …   Medical dictionary

  • TPMT — • thiopurine methyltransferase …   Dictionary of medical acronyms & abbreviations

  • Mercaptopurine — Systematic (IUPAC) name 3,7 dihydropurine 6 thione Clinical data Trade names Purinethol …   Wikipedia

  • Pharmacogenetics — The terms pharmacogenomics and pharmacogenetics tend to be used interchangeably, and a precise, consensus definition of either remains elusive. Pharmacogenetics is generally regarded as the study or clinical testing of genetic variation that… …   Wikipedia

  • Thiopurin-Methyltransferase — Bändermodell der TMPT nach PDB 2bzg …   Deutsch Wikipedia

  • Тамм, Риин — Риин Тамм эст. Riin Tamm …   Википедия

  • Methotrexate — Amethopterin redirects here. Not to be confused with aminopterin. Methotrexate Systematic ( …   Wikipedia

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