trichostatin

trichostatin
Any of a family of antifungal antibiotics that are histone deacetylase inhibitors

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  • Trichostatin A — drugbox IUPAC name = 7 [4 (dimethylamino)phenyl] N hydroxy 4,6 dimethyl 7 oxohepta 2,4 dienamide CAS number = 58880 19 6 ATC prefix = ATC suffix = PubChem = 444732 C=17 | H=22 | N=2 | O=2 smiles = CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C… …   Wikipedia

  • Histone deacetylase — Histone deacetylases (HDAC) (EC number 3.5.1) are a class of enzymes that remove acetyl groups from an ε N acetyl lysine amino acid on a histone. Its action is opposite to that of histone acetyltransferase.ubtypesHDAC proteins are found in three… …   Wikipedia

  • Nucleosom — Nukleosom: DNA (orange) und Histone (blau). Die erste Verpackungsstufe der DNA höherer Zellen ist ein Komplex aus DNA und Histonen, das so genannte Nukleosom. Von Ada und Donald Olins in elektronenmikroskopischen Darstellungen gequollener… …   Deutsch Wikipedia

  • Nukleosom — Übergeordnet Chromosom Untergeordnet DNA Histone …   Deutsch Wikipedia

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  • Fermentek — Infobox Company company name = Fermentek Biotechnology Ltd. company type = Private company foundation = 1995 location = Israel key people = Yosef Behrend , CEO industry = Biotechnology products = Special bioactive compounds for research divisions …   Wikipedia

  • Sirtuin — Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases/mono ADP ribosyltransferases found in organisms ranging from bacteria to humans. Named after the yeast silent mating type information regulation two… …   Wikipedia

  • Vorinostat — drugbox IUPAC name = N hydroxy N phenyl octanediamide CAS number = 149647 78 9 ATC prefix = ATC suffix = PubChem = 5311 DrugBank = DB02546 C = 14 | H = 20 | N = 2 | O = 3 molecular weight = 264.32 g/mol bioavailability = protein bound = 71%… …   Wikipedia

  • Histone deacetylase inhibitor — Histone deacetylase inhibitors (HDAC inhibitors, HDI) are a class of compounds that interfere with the function of histone deacetylase.Cellular Biochemistry / PharmacologyTo carry out gene expression, a cell must control the coiling and uncoiling …   Wikipedia

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