apurinic

apurinic
From which purines have been removed

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  • apurinic sites — Sites in DNA from which purines have been lost by cleavage of the deoxy ribose N glycosidic linkage …   Dictionary of molecular biology

  • apurinic acid — DNA from which the purine bases have been removed by mild acid treatment …   Medical dictionary

  • DNA-(apurinic or apyrimidinic site) lyase — Identifiers EC number 4.2.99.18 CAS number 61811 29 8 …   Wikipedia

  • APEX1 — APEX nuclease (multifunctional DNA repair enzyme) 1, also known as APEX1, is a human gene. PBB Summary section title = summary text = Apurinic/apyrimidinic (AP) sites (also called abasic sites ) occur frequently in DNA molecules by spontaneous… …   Wikipedia

  • AP endonuclease — An AP endonuclease is an enzyme that cuts a strand of DNA on the 5 side of an AP (apurinic/apyrimidinic) site, as the first step in DNA base excision repair (BER).AP endonucleases are divided into two families based on their homology to the… …   Wikipedia

  • Mutagenesis — (pronounced /mjuːtəˈdʒɛnɪsɪs/) is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be… …   Wikipedia

  • Depurination — In molecular genetics, depurination is an alteration of DNA in which the purine base (adenine or guanine) is removed from the deoxyribose sugar by hydrolysis of the beta N glycosidic link between them. After depurination, an apurinic site is… …   Wikipedia

  • Activation-Induced (Cytidine) Deaminase — (AID) is a 24 kDa enzyme that removes the amino group from the cytidine base in DNA.AID is currently thought to be the master regulator of secondary antibody diversification. It is involved in the initiation of three separate immunoglobulin (Ig)… …   Wikipedia

  • DNA polymerase beta — Polymerase (DNA directed), beta PDB rendering based on 1bno …   Wikipedia

  • AP — is a versatile abbreviation. It serves in cardiology to abbreviate angina pectoris (AP) and arterial pressure (AP). In endocrinology, it stands for the anterior pituitary (AP). And in anatomy, AP means anteroposterior, i.e., from front to back. * …   Medical dictionary

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